Experimental Design Essay Example | Topics and Well Written Essays - 500 words

Experimental Design - Essay Example c troponin levels and electrocardiograms were taken at the time of admission and then daily during the first week, subsequently on alternate months and then on a weekly basis, up to the discharge or demise of the patient in all patients that were admitted into the combined fifteen-bed university-affiliated surgical and medical intensive care unit for a period of two months. In addition to this data, additional data was collected from the patient medical chart, the ICU computerized clinical information system, and the hospital laboratory system in case report forms and then entered into an Excel program for statistical analysis. The main constituents of the statistical analysis consisted of the comparing of continuous variables employing the Kruskall-Wallis non-parametric tests and the Mann-Whitney paired test for the purpose of exploring the differences in groups. Categorical variables were analyzed using Pearson Chi-square tests or Fisher’s exact tests depending on appropriateness of the test. Screening investigations of cardiac troponin levels with ECGs helped to detect more myocardial infarction than through clinical diagnosis alone. Yet the length of stay of the patients in the intensive care unit and the hospital and the mortality rates remained the same as was experienced with patients whose myocardial infarction was detected by the ICU team and by screening. The study was conducted only for two month period in all patients admitted into the intensive care unit, which led to getting an evaluation of only of 103 patients. The sample size is too small for getting suitable results that are valid and acceptable. The problem of validity is pronounced, as there is variability of the association of elevated of elevated cardiac troponins in critically ill patients with mortality and other adverse outcomes, which calls for a larger sample size. This problem is accepted by the authors. Elevated cardiac troponin levels are frequently seen in critically ill